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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79178 | WRN inhibitor 2 | DNA/RNA Synthesis | |
WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1]. | |||
T22980 | MIRA-1 | p53 Activator VIII,1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione,(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate,NSC 19630,WRN Helicase Inhibitor | DNA/RNA Synthesis , p53 |
MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activity with an IC50 of 20 µM. | |||
T72108 | Werner syndrome RecQ helicase-IN-2 | ||
Werner syndrome RecQ helicase-IN-2 (example 57), a potent inhibitor of the Werner syndrome RecQ DNA helicase enzyme (WRN), holds potential for use in cancer research. |